IUI vs. IVF: Which One Should You Go For? | Gleneagles Hospitals Malaysia
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IUI vs. IVF: Which One Should You Go For?

01 October 2025 · 6 mins read

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Which fertility treatment suits you? Learn more about IUI and IVF, their differences, effective rates, and costs. Visit a fertility clinic in Malaysia today.

Couples facing infertility problems constantly face the tough decision of picking between two common fertility treatments: Intrauterine Insemination (IUI) and In Vitro Fertilisation (IVF). Both methods are created to help infertile couples or individuals achieve pregnancy but vary in terms of procedure, cost, and effective rates. To whom that considers the treatment, it is important to be well informed of the main differences between IUI and IVF to make the final decision. This article examines both options and helps you select the best fertility treatment.

An Overview of IUI

A fertility treatment called Intrauterine Insemination (IUI) involves putting sperm directly into a woman’s uterus approximately the ovulation period to elevate the chances of fertilisation. This procedure is normally performed when there is a mild male fertility issue, unexplained fertility, or when a woman has ovulation issues. It is a minimally invasive procedure, and the sperm used in IUI can be taken from a partner or a sperm donor.

IUI is usually considered the first option of fertility treatment for couples going through infertility problems. It is quite simple compared to IVF and can be performed with or without fertility medications to stimulate the ovaries. Once injected into the uterus, the sperm is washed and prepped to elevate the chances of effective fertilisation. 

The success rate of IUI is dependent on factors such as age, underlying fertility issues, and fertility medication usage. IUI has an average success rate of 10–20% per cycle and it is also usually more affordable compared to IVF.

An Overview of IVF

An advanced fertility treatment called In-Vitro Fertilisation (IVF) involves extracting eggs from a woman’s ovaries and fertilising them out of the body with sperm in a lab. The embryo(s) are then implanted into the woman’s uterus once fertilisation happens. IVF is usually recommended for people or couples going through serious fertility issues, such as blocked fallopian tubes, low sperm count, or endometriosis.

The IVF procedure starts with stimulating the ovaries to produce multiple eggs. A procedure called egg retrieval will then retrieve the eggs. The sperm is also collected, and both insemination and fertilisation are done in a lab. After the formation of the embryos, they are monitored for growth before being sent to the uterus.

One of the main benefits of IVF is its high success rate. The success rate for women under 35 is approximately 40%, but this can decrease with age or underlying health conditions. Moreover, IVF also makes it possible to genetically screen embryos, which can be beneficial for people who run the risk of inheriting genetic disorders. However, IVF is notably more pricey than IUI, and the process is more complex and time-consuming.

Comparison of IUI and IVF

Both purposes of IUI and IVF target to elevate pregnancy chances, but they vary in terms of complexity, cost, and success rates.

Procedure Complexity

  • IUI is less invasive and normally has fewer steps involved. During ovulation, the sperm is put into the uterus, only basic monitoring and a short office visit are required.
  • The IVF process on the other hand is much more involved, which includes hormonal stimulation, egg retrieval, and embryo transfer.

Success Rates

  • IUI success rates are lower than IVF, specifically for women beyond 35. If one’s fertility issues are mild, IUI is more effective.
  • The success rates of IVF are higher, particularly for people with more serious fertility issues or those going through genetic screening.

Making the Right Call

Deciding between IUI and IVF is greatly dependent on the particular fertility issues you face, your age, and your budget. IUI may be the most suitable choice if you experience mild fertility issues, such as unexplained infertility or ovulation issues. IVF is normally recommended for people or couples who experience serious fertility challenges, such as blocked fallopian tubes, male factor infertility, or notable age-related decline in fertility.

You can receive personalised guidance through a consultation from a fertility clinic in Malaysia. A fertility specialist will first evaluate your situation, discuss the available options, and recommend the most appropriate treatment. Gleneagles Hospitals, with their advanced fertility programs and expert team, can help decide whether IUI or IVF is the best approach for your new journey to parenthood.

Frequently Asked Questions about Fertility Treatments

1. Which emotional difficulties arise when coping with infertility?

Stress, anxiety, depression, or feelings of inadequacy are what some couples may experience. Seeking support from counsellors or joining fertility support groups can help.

2. What is the duration of each treatment?

The duration of IUI is normally just a couple of days, while IVF can take a few weeks, including ovarian stimulation, egg retrieval, and embryo transfer.

3. Can someone with irregular periods still conceive?

Yes, but it can be harder to predict ovulation if one has irregular periods. However, there are treatments to help regulate cycles and improve conception chances.

4. How can I increase the chances that IUI or IVF will be successful?

Keeping a healthy lifestyle, following the medication advice given by your fertility doctor, and stress management can help increase your chances. Embryo genetic screening may also be helpful for IVF.

Schedule an Appointment at Gleneagles Hospitals

It does not matter if you are considering Intrauterine Insemination (IUI) or In-Vitro Fertilisation (IVF), you can choose which treatment may be the best for your needs with the help of an early consultation.

If you have questions about IUI or IVF, or if you are prepared to start your fertility treatment, contact us today to schedule an appointment at your nearest Gleneagles Hospital. Our expert team can provide personalised advice and help you determine the best course of action. Schedule an appointment with our fertility clinic today and take the first step toward expanding your family.

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